Why the P-Shot Has a High Safety Profile
The P-Shot's exceptional safety record is largely due to its autologous nature — using your own blood. Since no foreign substances are introduced, allergic reactions and immune responses are virtually impossible. The procedure has no systemic side effects, does not interact with medications, and requires no general anaesthesia.
What the Research Says About P-Shot Safety
Multiple studies on PRP penile injections have reported no serious adverse events. A 2020 systematic review found that PRP injection for ED was associated with minimal complications — primarily mild bruising and temporary swelling. No study in the peer-reviewed literature has reported serious long-term harms from properly administered PRP.
Risks to Be Aware Of
The main risks are procedural rather than pharmacological: infection (prevented by sterile technique), vascular injury (extremely rare with a skilled practitioner), and nodule formation (uncommon, typically resolves). Choosing a medically qualified, experienced practitioner is the single most important safety factor.
Who Should Not Have a P-Shot?
The P-Shot is not recommended for: men with bleeding disorders or on blood thinners, those with active penile infections or skin conditions, men with certain clotting disorders, or those with very low platelet counts. A thorough medical consultation will identify any contraindications.
How to Choose a Safe P-Shot Clinic
Key factors: the doctor performing the procedure should be medically qualified (urologist or trained GP), the clinic should use FDA-cleared PRP centrifuge systems, sterile single-use equipment should be standard, and post-procedure support should be available. Our Turkey clinic meets all of these criteria and has treated over 1,000 patients without a single serious complication.