Comparison
Evidence status: ExperimentalP-Shot vs Stem Cell Therapy for Erectile Dysfunction
What is the difference between P-Shot and stem cell therapy for ED?
P-Shot injects platelet-rich plasma prepared from your blood. Stem-cell therapy uses cells or a cell-based preparation. Both are experimental for ED, and current evidence cannot show that one is better. Preparation and protocols differ between clinics, so ask exactly what is injected and what evidence supports it.
Key fact: The 2026 EAU guideline considers the evidence for stem-cell therapy in ED insufficient for routine clinical use. (European Association of Urology, 2026; page updated )
Private & confidential enquiry. You do not need to call.
P-Shot vs stem cells at a glance
| Aspect | P-Shot (PRP) | Stem cell therapy |
|---|---|---|
| What is injected | Platelet-rich plasma from your blood | Cells or a cell-based preparation |
| Preparation | Blood draw and centrifuge | Varies by source and processing method |
| Standardisation | Protocols vary | Sources, methods and regulation vary widely |
| Evidence | Mixed trials; EAU: clinical trials only | Small, varied studies; EAU: insufficient evidence |
| Assessment required | Yes | Yes |
Read the full guides
P-Shot / PRP
ExperimentalPlatelet-rich plasma is prepared from your own blood and injected into penile tissue after numbing.
Read the guide →Stem Cell Therapy
ExperimentalA cell-based preparation is injected into penile tissue with the aim of supporting tissue repair.
Read the guide →Exosome Therapy
ExperimentalExosomes are tiny cell-released vesicles being studied for signalling that may support tissue repair.
Read the guide →Your physician
Dr. Niyazi Umut Özdemir
Urological Surgeon, UZ Clinic Antalya
Responsible for assessment and treatment planning at the clinic, with a clinical focus on male sexual health and penile rehabilitation.
Rated 4.5 on Google (47 reviews, as of 2 Oct 2026)Qualifications
- • Medical education at Ege University
- • Specialisation in urology
- • Turkish Association of Urology board certification
- • Clinical practice in Antalya, Turkey
Clinical focus
- • Erectile dysfunction assessment and treatment planning
- • Penile rehabilitation
- • Vasculogenic (blood-flow related) erectile dysfunction
- • Shockwave therapy, PRP and regenerative approaches
Education and roles
- • Ege University Faculty of Medicine (2000); urology specialisation, Ege University (2005)
- • Head of the Antalya branch, CİSED
Professional memberships
- • Turkish Urological Association
- • Society of Urological Surgery (Ürolojik Cerrahi Derneği)
- • European Association of Urology (EAU)
- • Turkish Andrology Association
- • Aegean Urological Association (Ege Üroloji Derneği)
- • Ankara Urologists Association
Ask the urologist about your case
Send your history and the clinic will advise which options may be relevant. Suitability is decided after medical assessment.
Frequently asked questions
Which is more effective, PRP or stem cells?
Evidence cannot show that either is superior. Both are experimental for ED.
Is stem cell therapy more expensive?
Prices differ by provider and protocol. A higher price does not establish a better outcome.
Sources
- EAU Guidelines on Sexual and Reproductive Health: Management of Erectile DysfunctionEuropean Association of Urology, 2026 · Guideline
- Erectile Dysfunction: AUA GuidelineAmerican Urological Association, 2018 · Guideline
- PRP for the Treatment of Erectile Dysfunction (NCT04350125)ClinicalTrials.gov, Current record · Trial registry
Related guides
Send your case for confidential review
You do not need to know which treatment you need. Share a few details and the clinic can advise which options may be relevant to your case.
- 1. Send your caseAbout 2 minutes, private.
- 2. Coordinator contacts youBy WhatsApp, phone or email.
- 3. Doctor assessmentThe urologist decides suitability.
Private & confidential enquiry. You do not need to call.
This page provides general information and does not diagnose ED or decide whether a treatment is suitable for you. Suitability and expected benefit vary between patients and are decided after medical assessment. Treatments described as experimental or investigational are discussed with full informed consent. Seek urgent care for chest pain, new neurological symptoms, penile injury or an erection lasting more than four hours.