Safety
Evidence status: ExperimentalP-Shot Side Effects and Risks
What are the side effects of the P-Shot?
Reported side effects in studies have generally been minor: temporary pain, tenderness, bruising, redness or swelling. Bleeding, haematoma and infection are possible, and small trials cannot reliably quantify rare events or long-term effects. Using your own blood avoids rejection but does not make the procedure risk-free.
Key fact: Reported adverse events in PRP studies have generally been minor, but trials are too small to define uncommon risks confidently. (International Journal of Impotence Research / PubMed, 2024; page updated )
Private & confidential enquiry. You do not need to call.
Possible effects and risks
Expected or common
Temporary injection pain, tenderness, bruising, redness or swelling.
Bleeding-related
Higher risk with anticoagulants, antiplatelets or bleeding disorders.
Infection
Possible with any injection if sterile technique is not followed.
Uncertain or uncommon
Small trials cannot reliably quantify rare events or long-term effects on penile tissue.
Discuss suitability before treatment
- Active infection, skin lesions or current genital symptoms.
- Bleeding disorders, low platelet counts or medicines that affect clotting.
- Cancer treatment, immune suppression or other major medical conditions.
- Allergy or prior reaction to local anaesthetic.
- Unexplained penile pain, curvature, a lump or suspected Peyronie's disease.
Your physician
Dr. Niyazi Umut Özdemir
Urological Surgeon, UZ Clinic Antalya
Responsible for assessment and treatment planning at the clinic, with a clinical focus on male sexual health and penile rehabilitation.
Rated 4.5 on Google (47 reviews, as of 2 Oct 2026)Qualifications
- • Medical education at Ege University
- • Specialisation in urology
- • Turkish Association of Urology board certification
- • Clinical practice in Antalya, Turkey
Clinical focus
- • Erectile dysfunction assessment and treatment planning
- • Penile rehabilitation
- • Vasculogenic (blood-flow related) erectile dysfunction
- • Shockwave therapy, PRP and regenerative approaches
Education and roles
- • Ege University Faculty of Medicine (2000); urology specialisation, Ege University (2005)
- • Head of the Antalya branch, CİSED
Professional memberships
- • Turkish Urological Association
- • Society of Urological Surgery (Ürolojik Cerrahi Derneği)
- • European Association of Urology (EAU)
- • Turkish Andrology Association
- • Aegean Urological Association (Ege Üroloji Derneği)
- • Ankara Urologists Association
Ask the urologist about your case
Send your history and the clinic will advise which options may be relevant. Suitability is decided after medical assessment.
Frequently asked questions
Is the P-Shot safe?
Reported side effects have mostly been minor, but studies are small. The doctor explains risks and who should not have it.
What if I take blood thinners?
Tell the doctor. Blood thinners can raise the risk of bleeding and may mean the P-Shot is unsuitable.
Sources
- EAU Guidelines on Sexual and Reproductive Health: Management of Erectile DysfunctionEuropean Association of Urology, 2026 · Guideline
- Platelet-rich Plasma for the Treatment of Erectile Dysfunction: A Randomised Placebo-controlled TrialThe Journal of Urology / PubMed, 2023 · Randomised trial
- PRP Intracavernosal Injections for Primary Organic ED: Systematic Review and Meta-analysisInternational Journal of Impotence Research / PubMed, 2024 · Systematic review
Related guides
Send your case for confidential review
You do not need to know which treatment you need. Share a few details and the clinic can advise which options may be relevant to your case.
- 1. Send your caseAbout 2 minutes, private.
- 2. Coordinator contacts youBy WhatsApp, phone or email.
- 3. Doctor assessmentThe urologist decides suitability.
Private & confidential enquiry. You do not need to call.
This page provides general information and does not diagnose ED or decide whether a treatment is suitable for you. Suitability and expected benefit vary between patients and are decided after medical assessment. Treatments described as experimental or investigational are discussed with full informed consent. Seek urgent care for chest pain, new neurological symptoms, penile injury or an erection lasting more than four hours.