Evidence review
Evidence status: ExperimentalPRP for Erectile Dysfunction: What the Evidence Shows
Can PRP help erectile dysfunction?
Some studies report improved erectile function after penile PRP injections, but results are mixed and protocols vary. A 2023 placebo-controlled trial found no benefit over placebo. The 2026 EAU guideline says PRP for ED should be used only in a clinical-trial setting, so any use outside trials is experimental and should follow full consent.
Key fact: The 2026 EAU guideline says intracavernosal PRP for erectile dysfunction should be used only in a clinical-trial setting. (European Association of Urology, 2026; page updated )
Private & confidential enquiry. You do not need to call.
Key takeaways
- Evidence is mixed, with small studies and different protocols.
- Guidelines do not currently recommend PRP for routine ED care.
- A specialist assessment shows whether PRP is even relevant for your type of ED.
What the research shows
| Source | What it reports |
|---|---|
| 2026 EAU guideline | PRP for ED should be used only in a clinical-trial setting. |
| Randomised trials (for example Poulios 2021) | Some report improved erectile-function scores compared with placebo. |
| 2023 randomised placebo-controlled trial (Masterson) | No significant difference from placebo and no Doppler improvement through six months. |
| Systematic review and meta-analysis (Panunzio 2024) | Promising signals, with large variation in dose, preparation and study quality. |
Why results differ
- Studies are often small and short.
- PRP is prepared in different ways, so platelet concentration and activation vary.
- Men studied differ in age, ED cause and severity.
- Best candidates, number of sessions and long-term benefit are still unknown.
Compare with other options
Shockwave Therapy (EdSWT)
EmergingLow-intensity shockwaves are applied to the penis. The proposed aim is to support blood-flow related pathways.
Read the guide →Stem Cell Therapy
ExperimentalA cell-based preparation is injected into penile tissue with the aim of supporting tissue repair.
Read the guide →Exosome Therapy
ExperimentalExosomes are tiny cell-released vesicles being studied for signalling that may support tissue repair.
Read the guide →Penile Rehabilitation Programme
IndividualisedA stepwise plan that may combine medication, devices and other therapies according to the cause.
Read the guide →Your physician
Dr. Niyazi Umut Özdemir
Urological Surgeon, UZ Clinic Antalya
Responsible for assessment and treatment planning at the clinic, with a clinical focus on male sexual health and penile rehabilitation.
Rated 4.5 on Google (47 reviews, as of 2 Oct 2026)Qualifications
- • Medical education at Ege University
- • Specialisation in urology
- • Turkish Association of Urology board certification
- • Clinical practice in Antalya, Turkey
Clinical focus
- • Erectile dysfunction assessment and treatment planning
- • Penile rehabilitation
- • Vasculogenic (blood-flow related) erectile dysfunction
- • Shockwave therapy, PRP and regenerative approaches
Education and roles
- • Ege University Faculty of Medicine (2000); urology specialisation, Ege University (2005)
- • Head of the Antalya branch, CİSED
Professional memberships
- • Turkish Urological Association
- • Society of Urological Surgery (Ürolojik Cerrahi Derneği)
- • European Association of Urology (EAU)
- • Turkish Andrology Association
- • Aegean Urological Association (Ege Üroloji Derneği)
- • Ankara Urologists Association
Ask the urologist about your case
Send your history and the clinic will advise which options may be relevant. Suitability is decided after medical assessment.
Frequently asked questions
What is a PRP penis injection?
A PRP penis injection, also called the P Shot or penile PRP, injects platelet-rich plasma prepared from your own blood into penile tissue. It is experimental for ED, and results are mixed.
Is PRP approved for erectile dysfunction?
PRP for ED is not part of standard guideline care. The EAU says it should be used only in clinical trials.
Is PRP better than Viagra?
No evidence shows that. PDE5 inhibitors have established evidence and are first-line for many men. PRP is experimental.
Who might still consider PRP?
Some well-informed men with organic ED, after discussing established options, may choose to explore it. The doctor decides after assessment.
Sources
- EAU Guidelines on Sexual and Reproductive Health: Management of Erectile DysfunctionEuropean Association of Urology, 2026 · Guideline
- Erectile Dysfunction: AUA GuidelineAmerican Urological Association, 2018 · Guideline
- PRP Intracavernosal Injections for Primary Organic ED: Systematic Review and Meta-analysisInternational Journal of Impotence Research / PubMed, 2024 · Systematic review
- Platelet-rich Plasma for the Treatment of Erectile Dysfunction: A Randomised Placebo-controlled TrialThe Journal of Urology / PubMed, 2023 · Randomised trial
- Platelet-Rich Plasma Improves Erectile Function: A Randomised Placebo-controlled TrialThe Journal of Sexual Medicine / PubMed, 2021 · Randomised trial
Related guides
Send your case for confidential review
You do not need to know which treatment you need. Share a few details and the clinic can advise which options may be relevant to your case.
- 1. Send your caseAbout 2 minutes, private.
- 2. Coordinator contacts youBy WhatsApp, phone or email.
- 3. Doctor assessmentThe urologist decides suitability.
Private & confidential enquiry. You do not need to call.
This page provides general information and does not diagnose ED or decide whether a treatment is suitable for you. Suitability and expected benefit vary between patients and are decided after medical assessment. Treatments described as experimental or investigational are discussed with full informed consent. Seek urgent care for chest pain, new neurological symptoms, penile injury or an erection lasting more than four hours.